COVID-19 hastalarında uzamış D-dimer yüksekliği ve herediter trombofili arasındaki ilişki

Aim: To compare the D-Dimer levels in patients with mild COVID-19 disease and without hereditary thrombophilia.
 Material Method: Factor V Leiden (G1691A) mutation, methylene tetrahydrofolate gene mutation (C677T, A1298C), PAI-1 (4G-5G) FXIII (V34L) mutations were examined all included study for various reasons such as recurrent miscarriage venous embolism. Patients any thrombophilia group, while control group. D-dimer of also analyzed second time at least 25 days after admission. All had received previously two doses BioNTech-Pfizer or CoronaVac vaccines.
 Results: A total 158 patients, 46 (29.1%) male 112 (70.9%) female, study. The mean age was 39.08 ± 9.09 years. 121 33 (27.3%) men 88 (72.7) women, first 37 13 (35.1%) 24 (64.9%) who did not have mutations, taken Of thrombophilia, 47 (38.8%) Leiden, 63 (52.1%) MTHFR 32 (26.4%) 12 (9.9%) mutations. When values both groups 20-35 admission to hospital, level group 667.26 ±354.11 369.76±173.45 (P=0.031). 23 2 found be above 1000ng/ml when they came control. 
 Conclusion: It should kept mind that if there is prolonged newly emerging elevation mild-moderate symptoms, these may thrombophilia.